PROSPECTS OF PHARMACOLOGICAL TREATMENT OF VASCULAR DEMENTIA IN PATIENTS WITH ARTERIAL HYPERTENSION
Keywords:
vascular dementia, arterial hypertension, vegetative dystonia syndrome, headacheAbstract
The article presents research data from 60 patients with vascular dementia. All subjects were divided into 2 groups: 1st group - 30 patients who received choline alfoscerate on the background of basic therapy; and group 2 - 30 patients who received only basic therapy. The effectiveness of therapy was evaluated twice: before treatment and on day 40 of treatment. The status was assessed using the VAS scale (visual-analogue scale for pain), according to the questionnaire for identifying vegetative disorders and determining the vegetative dystonia syndrome (VDS), according to the severity of vegetative reactivity according to the Danyini-Ashner test, and the Hamilton anxiety and depression test. A reliable nootropic effect of the drug was revealed, as well as its effect on cerebrosthenic and somatovegetative manifestations. There were no serious adverse events requiring additional measures.
References
1. Gusev EI, Belousov Yu.B., Boyko AN. and other General principles of pharmacoeconomic research in neurology: Method. recommendations. M.; Publisher E. Razumova, 2003.-56 p.
2. Damulin I.V. Alzheimer's Disease and Vascular Dementia / Ed. N.N. Yah. - M., 2002. -- S. 85.
3. Damulin, I. V. Vascular dementia: pathogenesis, diagnosis and treatment / I. V. Damulin // Farmateka. - 2010. - No. 7. - S. 13–18.
4. Kamchatnov PR., Chugunov A.V., Volovets S.A., Umarova H.Ya. Combination therapy of discirculatory encephalopathy. Consilium medicum. 2005; 7 (8): 686-92.
5. Kamchatnov P.R. Chronic disorders of cerebral circulation, the possibility of metabolic therapy. - breast cancer, volume 16, No. 5, 2008 - p. 274-276.
6. Nikolskaya I.N., Guseva I.A., Bliznevskaya E.V. et al. The role of anxiety disorders in hypertension and the possibility of their correction // Attending physician. - 2007. - No. 3. - S. 89–91.
7. Piradov M.A. Antiplatelet therapy in the prevention of repeated ischemic strokes. - Breast cancer, 2003, volume 11, number 12 with. 696-698.
