MOLECULAR GENETIC FEATURES OF THYROID CANCER IN RESIDENTS OF THE KHOREZM REGION
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thyroid cancerAbstrak
Background. Thyroid cancer (TC) is the most common malignant tumor of the endocrine system and demonstrates pronounced molecular heterogeneity. Genetic alterations such as BRAF, RAS, RET/PTC, NTRK fusions, and TERT promoter mutations play a key role in tumor initiation, progression, and prognosis.##submission.citations##
1. Haugen BR et al. 2015 American Thyroid Association Management Guidelines. Thyroid. 2016.
2. Agrawal N et al. Integrated genomic characterization of papillary thyroid carcinoma. Cell. 2014.
3. WHO Classification of Tumours of Endocrine Organs. 5th ed. 2022.
4. Xing M. Molecular pathogenesis of thyroid cancer. Endocr Rev. 2020.
5. Liu R, Xing M. TERT promoter mutations in thyroid cancer. Endocr Relat Cancer. 2016
6. Ражапов, А. А. (2024). ҚАЛҚОНСИМОН БЕЗ МЕДУЛЛЯР КАРЦИНОМАЛАРИНИНГ ПАТОЛОГОАНАТОМИК ТАВСИФИ. Журнал гуманитарных и естественных наук, (12), 73-75.
7. Раджапов, А. А. (2024). МОРФОМЕТРИЧЕСКИЕ ПОКАЗАТЕЛИ ЗЛОКАЧЕСТВЕННЫХ ОПУХОЛЕЙ ЩИТОВИДНОЙ ЖЕЛЕЗЫ. Международный журнал научной педиатрии, 3(6), 623-626.
8. Rajapov, A. A. (2023). Morphometric Changes of Thyroid Cancer in the Regions Along the Aral Sea. Central Asian Journal of Medical and Natural Science, 4(5), 994-997.
9. Rajapov A.A., & Karimov R.X. (2025). OROL BO'YI MINTAQASIDA QALQONSIMON BЕZ PAPILLYAR SARATONLARINING PATOMORFOLOGIYASI. JANUBIY OROL BO'YI TIBBIYOT JURNALI, 1(4), 785–790. https://doi.org/10.5281/zenodo.18063608