IMMUN AMNEZIYA VA QIZAMIQ EPIDEMIYASI: GLOBAL XAVFLAR, MATEMATIK MODELLAR VA AMALIY TAVSIYALAR
Kalit so‘zlar:
qizamiq, immun amneziya, emlash qamrovi, yashirin davr muddati modellari, antibakterial rezistentlikAbstrak
Qizamiq virusi (Measles virus) — juda yuquvchan virus bo‘lib, klinik jihatdan katta zarar keltirib chiqaradi. Keyingi yillarda dunyo bo‘ylab qizamiq holatlarining ko‘payishi va emlash qamrovining pasayishi kuzatilmoqda. Bundan tashqari, qizamiq infeksiyasidan keyin immun amneziya (measles-induced immune amnesia) fenomeni immun sistema xotirasining qisman o‘chishi bilan bog‘langan bo‘lib, bu boshqa infeksiyalarga nisbatan sezgirlik oshishiga olib kelishi mumkin. Ushbu maqolada immun amneziya fiziopatologiyasi, uning populyatsiya darajasidagi oqibatlari, matematik modellar orqali beriladigan prognozlar va amaliy epidemiologik choralar to‘g‘risida sintetik, ilmiy tahlilni taqdim etamiz. Maqsad — ilmiy hamjamiyat, epidemiologlar va sog‘liqni saqlash siyosatchilari uchun asoslangan, amaliyotga mos tavsiyalar berish.
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Havolalar
1. JSST (World Health Organization) — vaksinalar va qizamiq bo‘yicha tavsiyalar;
2. Centers for Disease Control and Prevention (CDC) — genomik kuzatuv va respirator viruslar bo‘yicha ma’lumotlar;
3. Bir qator tadqiqotlar: measles-induced immune amnesia (seriyali epidemiologik va molekular tadqiqotlar).
4. World Health Organization (WHO). “Measles Fact Sheet.” 2024.
5. WHO. “Measles vaccines: WHO position paper.” Weekly Epidemiological Record, 2019.
6. Centers for Disease Control and Prevention (CDC). “Measles (Rubeola): Clinical Overview.” 2024.
7. CDC. “Measles — United States and Global Epidemiology.” 2023.
8. Mina, M. J., et al. “Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens.” Science, 2019.
9. Laksono, B. M., et al. “Measles immune suppression: lessons from the 2019 outbreaks.” The Lancet Infectious Diseases, 2020.
10. PLOS Pathogens. “Long-term immunologic effects of measles infection.” 2022.
11. The Lancet. “Global resurgence of measles and public health implications.” 2021.
12. European CDC (ECDC). “Measles: Risk Assessment Report.” 2023.
