АНДИЖОН ВИЛОЯТИДА ОИВ ИНФЕКЦИЯСИ БИЛАН ЯШОВЧИ БЕМОРЛАРДА АНТИРЕТРОВИРУС ТЕРАПИЯНИНГ УЗОҚ МУДДАТЛИ КЛИНИК САМАРАДОРЛИГИНИ БАҲОЛАШ
Kalit so‘zlar:
ОИВ инфекцияси, антиретровирус терапия, АРВТ, CD4 лимфоцитлари, вирус юкламасиAbstrak
615 нафар беморнинг ретроспектив маълумотлари таҳлил қилинди. Икки нуқтадаги вирус юкламаси мавжуд 501 беморда самарали даволаш улуши 57,3% ни ташкил этди. Содиқ беморларда клиник-иммунологик ва вирусологик натижалар яхшироқ бўлди. Кўп омилли моделда содиқликнинг йўқлиги вирусологик самарасизлик билан энг кучли боғлиқ омил сифатида қайд этилди.
##plugins.themes.default.displayStats.downloads##
Havolalar
1. World Health Organization. (2021). Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring: Recommendations for a public health approach. WHO. https://www.who.int/publications/i/item/9789240031593
2. UNAIDS. (2024). The urgency of now: AIDS at a crossroads. 2024 Global AIDS Update. https://www.unaids.org/en/resources/documents/2024/global-aids-update-2024
3. INSIGHT START Study Group. (2015). Initiation of antiretroviral therapy in early asymptomatic HIV infection. New England Journal of Medicine, 373, 795–807. https://doi.org/10.1056/NEJMoa1506816
4. Danel, C., et al. (2015). A trial of early antiretrovirals and isoniazid preventive therapy in Africa. New England Journal of Medicine, 373, 808–822. https://doi.org/10.1056/NEJMoa1507198
5. Cohen, M. S., et al. (2016). Antiretroviral therapy for the prevention of HIV-1 transmission. New England Journal of Medicine, 375, 830–839. https://doi.org/10.1056/NEJMoa1600693
6. World Health Organization. (2017). HIV drug resistance report 2017. WHO. https://www.who.int/publications/i/item/9789241512831
7. World Health Organization. (2025). WHO guideline on HIV service delivery: Updated guidance on integration and adherence. https://www.who.int/publications/i/item/9789240113879
8. World Health Organization. (2025). WHO updated recommendations on HIV clinical management: Recommendations for a public health approach. https://www.who.int/publications/i/item/9789240119468
9. Panel on Antiretroviral Guidelines for Adults and Adolescents. (2025). Guidelines for the use of antiretroviral agents in adults and adolescents with HIV. ClinicalInfo, NIH. https://clinicalinfo.hiv.gov/en/guidelines/adult-and-adolescent-arv
10. von Elm, E., et al. (2007). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies. PLoS Medicine, 4(10), e296. https://doi.org/10.1371/journal.pmed.0040296
