DEVELOPMENT OF CARDIOTOXIC COMPLICATIONS IN CANCER: THE SIGNIFICANCE OF CLINICAL AND HELIOGEOPHYSICAL FACTORS

Mualliflar

  • Muslimbek Yusupov First-Year Master's Student in Cardiology at Central Asian Medical University ##default.groups.name.author##
  • Abdulaziz Ergashev First-Year Master's Student in Cardiology at Central Asian Medical University ##default.groups.name.author##

Kalit so‘zlar:

Cancer, cardiotoxicity, cardiovascular system, chemotherapy, arterial hypertension

Abstrak

This article examines clinical and heliogeophysical factors associated with the development of cardiotoxic complications in cancer patients. Some anticancer treatments, including chemotherapy, targeted therapy, and radiotherapy, may have adverse effects on the cardiovascular system. The study considers the main clinical manifestations and risk factors of cardiotoxicity, as well as the importance of modern diagnostic approaches. Electrocardiography, echocardiography, and cardiac biomarkers play an important role in the early detection of changes in cardiac function. Particular attention is also given to the possible influence of heliogeophysical factors, including solar activity and geomagnetic fluctuations, on cardiovascular function. Early identification of cardiotoxic complications, assessment of individual risk factors, and regular cardiovascular monitoring are important for improving the safety of anticancer treatment. A comprehensive approach involving oncology and cardiology specialists may contribute to the prevention of severe cardiovascular complications and better management of cancer patients

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Havolalar

1. Lyon A.R., López-Fernández T., Couch L.S. et al. 2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association, the European Society for Therapeutic Radiology and Oncology and the International Cardio-Oncology Society // European Heart Journal. 2022. Vol. 43, № 41. P. 4229–4361.

2. Camilli M., Cipolla C.M., Dent S., Minotti G., Cardinale D.M. Anthracycline Cardiotoxicity in Adult Cancer Patients: JACC: CardioOncology State-of-the-Art Review // JACC: CardioOncology. 2024. Vol. 6, № 5. P. 655–677.

3. Lu Y., Pan W., Deng S. et al. Redefining the Incidence and Profile of Fluoropyrimidine-Associated Cardiotoxicity in Cancer Patients: A Systematic Review and Meta-Analysis // Pharmaceuticals. 2023. Vol. 16, № 4.

4. Mir A., Badi Y., Bugazia S. et al. Efficacy and safety of cardioprotective drugs in chemotherapy-induced cardiotoxicity: an updated systematic review and network meta-analysis // Cardio-Oncology. 2023. Vol. 9, № 1.

5. Wang V.A., Zilli Vieira C.L., Garshick E. et al. Solar Activity Is Associated With Diastolic and Systolic Blood Pressure in Elderly Adults // Journal of the American Heart Association. 2021. Vol. 10, № 21. Article e021006. — P. 1–10.

6. Manhas A., et al. Cardiovascular Toxicity in Cancer Therapy: Protecting the Heart while Combating Cancer // Current Cardiology Reports. 2024. Vol. 26, № 9. P. 953–971.

7. Gaisenok O., Gaisenok D., Bogachev S. The Influence of Geomagnetic Storms on the Risks of Developing Myocardial Infarction, Acute Coronary Syndrome, and Stroke: Systematic Review and Meta-analysis // Journal of Medical Physics. 2025. Vol. 50, № 1. P. 8–13.

Nashr qilingan

2026-09-27