INTEGRATED APPROACH TO THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER: FROM PSA SCREENING AND PROSTATE BIOPSY TO MRI, PSMA PET/CT AND RADICAL PROSTATECTOMY

Muzaffar Tukhtamishev; Mukhamedzarif Mukhamed Bakhadirhanov; Nodir Rakhimov; Shavkat Shavakhabov

Авторы

Muzaffar Tukhtamishev MD, PhD Urologist, RSSPMCU, Tashkent ,Uzbekistan Автор
Mukhamedzarif Mukhamed Bakhadirhanov MD, DSc Head of the Operating Department, RSSPMCU, Tashkent, Uzbekistan Автор
Nodir Rakhimov MD, PhD Deputy director, RSSPMCU, Tashkent ,Uzbekistan Автор
Shavkat Shavakhabov Deputy Director for Scientific Affairs, RSSPMCU, Tashkent, Uzbekistan Автор

Ключевые слова:

prostate cancer, PSA, MRI, PSMA PET/CT

Аннотация

Prostate cancer diagnosis requires an integrated assessment of PSA, MRI, biopsy and PSMA PET/CT. This review summarizes the role of these methods in detecting clinically significant cancer, determining disease extent and selecting patients for radical prostatectomy. The combination of PSA-based risk assessment, multiparametric MRI and targeted biopsy improves diagnostic accuracy, while PSMA PET/CT provides additional information for staging high-risk disease. An individualized diagnostic pathway may improve treatment selection and reduce unnecessary interventions.

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