CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS OF PARASITIC DISEASES IN ADULTS: DIAGNOSTIC PATTERNS AND STATISTICAL ANALYSIS

Aziza Elmurodova

Авторы

Aziza Elmurodova Associate Professor, PhD, Department of Hygiene No. 2, Bukhara State Medical Institute, Bukhara, Uzbekistan Автор

Ключевые слова:

parasitic diseases, helminthiasis, giardiasis, clinical epidemiology, eosinophilia

Аннотация

Parasitic infections remain a significant public health issue among adults, often presenting with vague or chronic clinical manifestations. This study evaluated the clinical and epidemiological features of parasitic diseases in 250 patients aged 18–60 years. Comprehensive laboratory and instrumental diagnostics revealed a high prevalence of giardiasis (38.4%) and ascariasis (22.0%), followed by echinococcosis (14.4%), enterobiasis (12.8%), and toxocariasis (8.4%). The predominant clinical presentation included dyspeptic syndrome (72.8%), abdominal pain (66.0%), asthenovegetative disorders (59.2%), and peripheral eosinophilia (54.0%). The integration of coprological, serological (ELISA), and ultrasound methods significantly improved diagnostic accuracy.

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Библиографические ссылки

1. Avdyukhina T.I., Konstantinova T.N. Giardiasis: modern concepts of diagnosis and therapy. Medical Parasitology and Parasitic Diseases, 2022; 4: 18–25.

2. Bronshtein A.M., Malyshev N.A. Modern problems of diagnosis and treatment of hepatobiliary helminthiases. Epidemiology and Infectious Diseases, 2021; 26(3): 124–131.

3. Garcia L.S., Arrowood M.J., Clay R.M. Diagnostic Medical Parasitology. 7th Edition. Washington D.C.: ASM Press, 2021. – 1250 p.

4. Hotez P.J., Aksoy S., Brindley P.J. Neglected tropical diseases and helminth infections in adults: global burden and clinical impact. PLOS Neglected Tropical Diseases, 2022; 16(4): e0010250.

5. Karimov H.Y., Ismoilov U.M. Immunological changes in parasitic diseases and methods for their correction. Infection, Immunity and Pharmacology, 2020; 2: 34–39.

6. Kravchenko K.B., Guzeeva T.M. Epidemiological surveillance of parasitic diseases under modern conditions. Journal of Microbiology, Epidemiology and Immunobiology, 2023; 100(2): 150–158.

7. Rasulov S.K., Ahmedova M.D. Clinical and epidemiological characteristics of giardiasis and other protozooses in adults. Medical Journal of Uzbekistan, 2023; 3: 45–50.

8. Sergiev V.P., Lobzin Yu.V., Kozlov S.S. Human Parasitic Diseases (Protozooses and Helminthiases). Saint Petersburg: Foliant, 2019. – 616 p.

9. Speich B., Croll D., Fuerst T. Effect of sanitation and water quality on soil-transmitted helminth infections: a systematic review and meta-analysis. The Lancet Infectious Diseases, 2023; 23(7): 821–833.

10. Thompson R.C.A., Ash A. Zoonotic parasites of global health importance. International Journal for Parasitology, 2020; 50(10-11): 799–810.

11. Tokmalaev A.K., Kozhevnikova G.M. Clinical Parasitology: Protozoan Infections and Helminthiases. Moscow: MIA, 2020. – 432 p.

12. Toshpulatov B.R., Mirzayeva S.A. Sanitary-epidemiological evaluation of parasitological indicators in spring and tap water. Journal of Healthcare Organization and Preventive Medicine, 2024; 1: 78–83.

13. World Health Organization. Preventive chemotherapy in human helminthiasis: coordinated use of anthelmintic drugs in control interventions. Geneva: WHO Press, 2021. – 148 p.

14. Yuldoshev A.A., Niyazov Z.M. Analysis of the prevalence of echinococcosis and nematodoses in Kashkadarya region. A New Day in Medicine, 2022; 5(43): 112–117.