ME’DA SARATONINING MORFOLOGIK PROFILI, O‘SISH SHAKLLARI VA PROGNOSTIK OMILLARINING KLINIK-MORFOLOGIK TAXLILI

Sharipa Fazilova; Aziza Satullayeva; Gulnara Abdirashitova

Authors

Sharipa Fazilova Urganch davlat tibbiyot instituti PhD dotsent. 2-Tibbiyot fakulteti dekani Author
Aziza Satullayeva Urganch davlat tibbiyot instituti 14.00.02-Morfologiya mutaxassisligi buyicha (PhD) tayanch doktorant Author
Gulnara Abdirashitova Qaraqolpogiston tibbiyot instituti IKP, endokrinologiya va psixiatriya kafedrasi katta assistent Author

Keywords:

me’da saratoni, adenokarsinoma, patomorfologiya, infiltrativ o‘sish, differensiatsiya darajasi

Abstract

Mazkur maqolada me’da saratoni bilan kasallangan bemorlarda o‘smaning morfologik tuzilishi, differensiatsiya darajalari va endoskopik o‘sish xususiyatlari kompleks tarzda tahlil qilingan. Tadqiqot jarayonida o‘smaning lokalizatsiyasi, infiltrativ o‘sish xususiyatlari, limfogen metastazlanish holatlari hamda klinik-laborator ko‘rsatkichlar baholandi. Tahlil natijalari past differensiyalashgan va infiltrativ o‘suvchi o‘smalarda agressiv kechish va yuqori invazivlik ko‘proq kuzatilishini ko‘rsatdi. Shuningdek, morfologik xususiyatlar kasallik prognozi va erta diagnostikasida muhim ahamiyat kasb etishi aniqlandi

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References

1. Давыдов М.И., Аксель Е.М. Статистика злокачественных новообразований в России и странах СНГ. – Москва: РОНЦ, 2020. – 282 с.

2. Каприн А.Д., Старинский В.В., Шахзадова А.О. Состояние онкологической помощи населению России в 2021 году. – Москва, 2021. – 239 с.

3. Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma // Acta Pathologica et Microbiologica Scandinavica. – 1965. – Vol. 64, №1. – P. 31–49.

4. Carneiro F., Guilford P. Hereditary diffuse gastric cancer and related conditions // Surgical Pathology Clinics. – 2017. – Vol. 10, №4. – P. 733–746.

5. Yamada T., Sugimoto M., Ota S. et al. Clinicopathological characteristics and prognosis of infiltrative gastric carcinoma // World Journal of Gastroenterology. – 2021. – Vol. 27, №14. – P. 1458–1471.

6. Kim J.H., Park S.S., Lee H.J. et al. Prognostic significance of infiltrative growth pattern in gastric adenocarcinoma // Annals of Surgical Oncology. – 2022. – Vol. 29, №3. – P. 1765–1774.

7. Japanese Gastric Cancer Association. Japanese gastric cancer treatment guidelines 2021 (6th edition) // Gastric Cancer. – 2022. – Vol. 25, №1. – P. 1–21.

8. World Health Organization. WHO Classification of Tumours of the Digestive System. 5th ed. – Lyon: IARC Press, 2019. – 635 p.

9. Correa P. Human gastric carcinogenesis: a multistep and multifactorial process // Cancer Research. – 1992. – Vol. 52, №24. – P. 6735–6740.

10. Sung H., Ferlay J., Siegel R.L. et al. Global cancer statistics 2024: GLOBOCAN estimates of incidence and mortality worldwide // CA: A Cancer Journal for Clinicians. – 2024. – Vol. 74, №1. – P. 1–35.