O'ZBEKISTONDA COVID-19 BILAN OG'RIGAN 2500 BEMORNING ASIMPTOMATIK VA SIMPTOMATIK GURUHLARINING EPIDEMIOLOGIK VA KLINIK XUSUSIYATLARI: BITTA MARKAZLI RETROSPEKTIV TADQIQOT

Baxodir Raximov; Baxtiyor Shodmonov; Erkin Sultonov

Authors

Baxodir Raximov Toshkent davlat tibbiyot universiteti, Atrof muhi gigiyeasi kafedrasi dotsenti, t.f.d., Toshkent sh., O‘zbekiston Author
Baxtiyor Shodmonov Toshkent davlat tibiyot universiteti Chirchiq filiali O’quv-uslubiy boshqarma boshlig’i, Chirchiq sh., O‘zbekiston Author
Erkin Sultonov Toshkent davlat tibbiyot universiteti, Atrof muhi gigiyeasi kafedrasi asisstenti, Toshkent sh., O‘zbekiston Author

Keywords:

COVID-19, SARS-CoV-2, asimptomatik, simptomatik, epidemiologik xususiyatlar

Abstract

Ushbu tadqiqot 2020-yilning aprel–avgust oylarida Toshkent tibbiyot akademiyasining ko'p tarmoqli klinikasida COVID-19 tashxisi bilan davolangan 2500 bemorning epidemiologik va klinik xususiyatlarini tavsiflovchi bitta markazli retrospektiv kesim tadqiqotidir. Bemorlar asimptomatik (n=989, 39,6%) va simptomatik (n=1511, 60,4%) guruhlarga bo'linib tahlil qilindi. Asimptomatik guruh yoshi kichikroq (me'dian 30 yosh) va xorijdan yuqtirishning ulushi yuqori (48,3%) ekanligi aniqlandi. Simptomatik guruhdagi bemorlar orasida eng ko'p uchraydigan alomatlar: charchoq (83,2%), yo'tal (58,5%) va harorat ko'tarilishi (56,6%) bo'ldi. Ikki guruh o'rtasidagi asosiy farqlar yosh, jins taqsimoti, inkubasiya davri, kasalxonaga tushish yo'llari va davolash taktikasida yaqqol namoyon bo'ldi. Natijalar COVID-19ning O'rta Osiyo mintaqasidagi dastlabki klinik manzarasini aks ettiradi va kelajakdagi profilaktika dasturlariga asos bo'lishi mumkin.

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References

1. Chen NS, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020;395(10223):507-513.

2. WHO Director-General's remarks at the media briefing on 2019-nCoV on 11 February 2020. https://www.who.int. Murojaat: 20.01.2022.

3. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506.

4. Teich VD, Klajner S, Almeida FAS, et al. Epidemiologic and clinical features of patients with COVID-19 in Brazil. Einstein (Sao Paulo). 2020;18:eAO6022.

5. Workman J. The proportion of COVID-19 cases that are asymptomatic in South Korea. Int J Infect Dis. 2020;96:398.

6. Jung CY, Park H, Kim DW, et al. Clinical Characteristics of Asymptomatic Patients with COVID-19: A Nationwide Cohort Study in South Korea. Int J Infect Dis. 2020;99:266-268.

7. Kim K, Choi JW, Moon J, et al. Clinical Features of COVID-19 in Uzbekistan. J Korean Med Sci. 2020;35(45):e404.

8. OECD (2021). Strengthening the frontline: How primary health care helps health systems adapt during the Covid-19 pandemic. https://read.oecd-ilibrary.org.

9. Interim guidelines for the management of patients infected with COVID-19 (6th ed.). The Ministry of Health of the Republic of Uzbekistan. 2020.

10. Responding to the COVID-19 pandemic: WHO's action in countries, territories and areas. Geneva: WHO; 2021.

11. Breslin N, Baptiste C, Gyamfi-Bannerman C, et al. Coronavirus disease 2019 infection among asymptomatic and symptomatic pregnant women. Am J Obstet Gynecol MFM. 2020;2(2):100118.

12. Shahriarirad R, Khodamoradi Z, Erfani A, et al. Epidemiological and clinical features of 2019 novel coronavirus diseases (COVID-19) in the South of Iran. BMC Infect Dis. 2020;20(1):427.

13. Wu B, Lei ZY, Wu KL, et al. Compare the epidemiological and clinical features of imported and local COVID-19 cases in Hainan, China. Infect Dis Poverty. 2020;9(1):143.

14. Tindale LC, Stockdale JE, Coombe M, et al. Evidence for transmission of COVID-19 prior to symptom onset. Elife. 2020;9.

15. He X, Lau EHY, Wu P, et al. Temporal dynamics in viral shedding and transmissibility of COVID-19. Nat Med. 2020;26(5):672-675.

16. Grasselli G, Zangrillo A, Zanella A, et al. Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy. JAMA. 2020;323(16):1574-1581.

17. Guan WJ, Ni ZY, Hu Y, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020;382(18):1708-1720.

18. Qian G, Yang N, Ma AHY, et al. COVID-19 Transmission Within a Family Cluster by Presymptomatic Carriers in China. Clin Infect Dis. 2020;71(15):861-862.

19. Yong SEF, Anderson DE, Wei WE, et al. Connecting clusters of COVID-19: an epidemiological and serological investigation. Lancet Infect Dis. 2020;20(7):809-815.

20. Qiu YY, Wang SQ, Wang XL, et al. Epidemiological analysis on a family cluster of COVID-19. Zhonghua Liu Xing Bing Xue Za Zhi. 2020;41(4):494-497.